Widespread abnormality of the γ-aminobutyric acid-ergic system in Tourette syndrome
نویسندگان
چکیده
منابع مشابه
Widespread abnormality of the γ-aminobutyric acid-ergic system in Tourette syndrome.
Dysfunction of the γ-aminobutyric acid-ergic system in Tourette syndrome may conceivably underlie the symptoms of motor disinhibition presenting as tics and psychiatric manifestations, such as attention deficit hyperactivity disorder and obsessive-compulsive disorder. The purpose of this study was to identify a possible dysfunction of the γ-aminobutyric acid-ergic system in Tourette patients, e...
متن کاملPaclitaxel Causes Electrophysiological Changes in the Anterior Cingulate Cortex via Modulation of the γ-Aminobutyric Acid-ergic System
OBJECTIVE The aim of this study was to elucidate any electrophysiological changes that may contribute to the development of neuropathic pain during treatment with the anticancer drug paclitaxel, particularly in the γ-aminobutyric acid (GABA) system. MATERIALS AND METHODS One hundred and eight Sprague-Dawley rats were used (untreated control: 43; vehicle-treated: 21, and paclitaxel-treated: 44...
متن کاملP145: The Role of γ-Aminobutyric Acid Receptor in The Social Anxiety Disorder
Social anxiety disorder (SAD) is the one of the most common anxiety disorders. Despite its high prevalence, the disorder is still considerably undiagnosed and untreated. The disease places a massive burden on patient’s lives, affecting not only their social interactions but also their educational and professional activities, thereby constituting a severe disability. γ-aminobutyric acid (GABA) s...
متن کاملTonic γ-aminobutyric acid-ergic activity in the hypothalamic arcuate nucleus is attenuated in the spontaneously hypertensive rat.
We tested the hypothesis that tonic γ-aminobutyric acid-ergic activity in the hypothalamic arcuate nucleus (ARCN) modulates blood pressure control and attenuation of this inhibitory activity contributes to hypertension in the spontaneously hypertensive rats (SHR). Mean arterial pressure (MAP), heart rate (HR), and greater splanchnic nerve activity (GSNA) were recorded in urethane-anesthetized, ...
متن کاملIdentification and characterization of γ-aminobutyric acid uptake system
State Key Laboratory of Microbial Resources and Dept. of Industrial 4 Microbiology and Biotechnology, Institute of Microbiology, Chinese Academy of 5 Sciences, Beijing 100101, PR China; Key Laboratory of Agricultural and 6 Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of 7 Sciences, Wuhan 430071, People's Republic of China 8 9 Running title 10 GABA uptake system in C....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Brain
سال: 2012
ISSN: 1460-2156,0006-8950
DOI: 10.1093/brain/aws104